• Lead Institution: Léon Bérard Center (Lyon)
• Key consortium members: Oscar Lambret Center (Lille), François Baclesse Center (Caen), CREATIS Laboratory – CNRS (Lyon)
• ESPACE aims to accelerate the development and implementation of 5P medicine (preventive, personalized, predictive, participatory, and evidence-based) in oncology through the use of artificial intelligence (AI).

📍Auvergne-Rhône-Alpes

• Led by the Gustave Roussy Institute
• Key consortium members: UNICANCER, Cancer Contribution, Léon Bérard Center, CEGEDIM, ODYSSEA, CPTS de la Bièvre, CPTS OCTAV, CPTS Val de Bièvre, CRCDC Ile-de-France, DAC 94, ELSAN  
• INTERCEPTION helps identify individuals at increased risk of cancer and offers them personalized prevention and screening services through a city-hospital partnership and a largely digital infrastructure.

📍Île-de-France

• Led by: Institut de Cancérologie de l’Ouest (ICO)
• Key consortium members: Bergonié Institute (IB), Mont de Marsan Hospital (CH MM), Digital Medical Hub (DMH)​​​​​
• ONCO-ATLANTIQUE is 100% dedicated to cancer care and improving complex care pathways: “from biomarkers to community-based care.” 

📍Pays de la Loire
 

• Led by: Assistance Publique - Hôpitaux de Paris
• Key consortium members: AP-HP, Medicen, Paris-Saclay University, 
• The BOpEX Campus, dedicated to the operating room, focuses on testing and co-developing digital solutions to improve the quality and safety of surgical and anesthesiology care, working conditions for operating room staff, and organizational efficiency.

📍Île-de-France

• Led by the Amiens-Picardie University Hospital Center (CHU AP)
• Key consortium members: Jules Verne University of Picardy (UPJV), Numih France, SATT Nord, innov’a
• GRECO EXPER aims to be a dynamic and collaborative hub for transforming healthcare through technological innovation, focusing on personalized robotic surgery and interventional medicine, and ensuring safe patient care pathways.

📍Hauts-de-France

• Led by: Streetlab
• Key consortium members: Quinze-Vingts National Ophthalmology Hospital (CHNO), VYV3 (VYV Group), Adolphe de Rothschild Foundation Hospital (HFAR), Valentin Haüy Association (AVH), Forum of Living Labs for Health and Independence (LLSA)
• Novavue aims to offer a range of complementary services to facilitate real-world testing and accelerate the market launch of innovative digital solutions for people with visual impairments, caregivers, and healthcare professionals.

📍Île-de-France

• Led by the Nice University Hospital
• Key consortium members: URPS Médecine libérale PACA, Association de Dermatologues Libéraux (ADL), Fédération Française de la Peau, INRIA Sophia-Antipolis, RESAH, Eurobiomed, Issé
• Skin aims to offer digital health experiments covering all aspects related to the skin—from medical conditions to cosmetic care—to improve patient care and provide effective tools for healthcare professionals. 

📍Provence-Alpes-Côte d’Azur

• Led by: GIP Genopole
• Key consortium members: Centre Hospitalier Sud-Francilien (CHSF), Société d’Accélération de Transfert Technologique (SATT) Paris-Saclay, European Institute of Innovation and Technology (EIT) Health France, Center for Study and Research on Intensive Diabetes Care (CERITD)
• The UXCARE Tiers-lieu focuses on innovative digital solutions designed to improve diabetes care. It facilitates the design of new products, services, and care pathways centered on user needs, and enables companies and healthcare facilities with technologically advanced solutions to test them in real-world settings and roll them out under optimal conditions.

📍Île-de-France

• Led by the Tours University Hospital
• Key members of the consortium: Orléans University Hospital, University of Tours, University of Orléans, the VYV3 Centre-Val de Loire mutual insurance union, the Centre-Val de Loire Regional Health Agency, the Healthcare Loire Valley association, and the Atlanpole Biotherapies competitiveness cluster
• ACCES CVL serves as a single regional gateway to simplify and accelerate the emergence of innovations by promoting coordinated care, as well as innovations targeting communication disorders for patients, their caregivers, and healthcare professionals.

📍Centre-Val de Loire

• Led by BioValley France
• Key consortium members: BioValley France, MedUniq Center, OpenCare Lab, Strasbourg University Hospitals, UGECAM Alsace, CPTS Mossig-Vignoble, Maison Sport-Santé de Strasbourg, Health Factory, ANAP, France asso Santé
• CARE Alsace aims to improve digital adoption among all citizens by involving them in digital health innovation processes.

📍Grand-Est

• Led by the Poitiers University Hospital
• Key consortium members: University of Poitiers, La Rochelle Hospital Center, the Greater Poitiers (Neoloji), La Rochelle, and Niortais (Altae) technology parks, and the Melioris Association (Niort).
• GSN aims to improve the health of the most vulnerable populations by promoting digital health innovations tailored to these groups and by mobilizing a variety of existing local expertise in the field of digital health.

📍Nouvelle-Aquitaine

• Led by: AP-HP
• Key consortium members: Université Paris Cité
• @Hôtel-Dieu fosters the development of innovation projects related to healthcare services and accelerates the testing and experimentation of innovations—which will be at the heart of tomorrow’s healthcare models—in real-world conditions. 

📍Île-de-France

• Led by the Lille University Hospital (CHRU)
• Key consortium members: the University of Lille, the URPS Médecins Libéraux, the Compagnie Tiers-Lieu, and Eurasanté
• IN CITU demonstrates, in real-world settings, the value of healthcare innovations to accelerate their rollout across the region and provide sustainable support for regional transformations, with a tangible impact on patient care pathways and the quality of life at work for healthcare professionals.

📍Hauts-de-France

• Led by: CAEN NORMANDIE University Hospital
• Key consortium members: University of Caen, Pole Tes, Normandy HealthTech, ISEN-OUEST, Normandie Incubation, Normandie Valorisation, CPTS Caen Couronne, CAEN la Mer, Gerontopôle
• The INS CAEN project aims to identify, test, and transform the patient journey over the long term for the benefit of patients, using innovative digital health solutions in the Normandy region.

📍Normandy

• Led by Rennes University Hospital
• Key consortium members: Saint-Thomas de Villeneuve Hospital Group, URPS Médecins Libéraux Bretagne, Guillaume Régnier Hospital Center, CPTS de la Seiche, CPTS Rennes Sud, CPTS de Brocéliande, CPTS du Pays de Redon, France Assos Santé Bretagne
• JINNOV accelerates the deployment of digital solutions that facilitate cooperation among healthcare stakeholders across a region, with the goal of improving patient care pathways, enhancing the quality of life for healthcare professionals at work, and supporting organizational transformation.

📍Brittany

• Led by: Nantes University Hospital
• Key consortium members: Atlanpole, University of Nantes
• LIEN Santé focuses on anticipating the integration of new digital solutions within a hospital of the future and is open to cross-disciplinary experimentation (laboratories, hospitals, primary care, data warehouses).

📍Pays de la Loire

• Led by Aésio Santé
• Key consortium members: Aésio Santé, Mines Saint-Étienne, Gérontopole Auvergne Rhône-Alpes, ALOESS, Nouvelles Technologies - AÉSIO Santé Méditerranée 
• MedTechLab is open to healthcare and medical-social institutions and is dedicated to testing digital health solutions as well as supporting research and development projects.

📍Auvergne-Rhône-Alpes

• Led by: Angers University Hospital
• Key consortium members: Angers University Hospital, 3 technology parks, the Angers Loire Métropole Economic Development Agency, 2 competitiveness clusters whose areas of excellence fall within the field of e-health, the Pays de la Loire Regional Consortium for e-Health Development, the VYV 3 Pays de la Loire-Centich group, Digital Pharma Lab, and AFM-Téléthon.
• MOBIS is dedicated to smart mobility in healthcare, organized around three main themes (mobility, patient journey, and healthcare region).

📍Pays de la Loire

• Led by: Martinique University Hospital
• Consortium: ARS Guyana, Tesis Grades (Reunion/Mayotte), I-NOVA Guadeloupe
• OCEAN CARE aims to optimize outpatient care pathways, reduce postoperative complications, and improve care coordination. It organizes the deployment and validation of digital solutions tailored to the needs of patients in overseas territories by targeting priority conditions in these regions.

📍Overseas Territories (Martinique, Guadeloupe, French Guiana, Réunion, Mayotte)

• Led by the Toulouse University Hospital
• Key consortium members: ASEI, Clinique Pasteur (Alliance Clinavenir)
• Toulouse Santé Numérique provides patient support throughout the entire care journey across a network of 129 facilities

📍Occitania

• Led by the Brest University Hospital
• Key consortium members: Biotech Santé Bretagne, Technopole Brest-Iroise, Les Patients s’engagent, Innoveo, Atlanpôle Biothérapies, Images et Réseaux, Le Village by CA
• W.INN is a hub for collaboration and innovation in digital health. It draws on regional strengths to develop pilot projects aligned with the institution’s strategy, digital technology, and cross-disciplinary expertise.

📍Brittany

• Led by the Bordeaux University Hospital
• Key consortium members: Centre Hospitalier de la Côte Basque, Centre Hospitalier Charles Perrens, University of Bordeaux, CATIE, UNITEC, Aquitaine Sciences Transfert
• Station E-Santé aims to address three major challenges that must be considered when developing useful and relevant digital solutions for users’ health: the challenge of effectiveness, the challenge of usage, and the challenge of integration.

📍Nouvelle-Aquitaine

• Led by UGECAM Ile-de-France and FLLSA
• Key consortium members: FLLSA, ICAM, IMT, INES, and UGECAM IDF
• Cap'Habilis aims to improve the quality of life for patients and people with disabilities receiving care, as well as the effectiveness of healthcare professionals, by combining the expertise of e-health stakeholders and healthcare professionals

📍Île-de-France

• Led by Coworkhit
• Key consortium members: 2 innovation centers—CoWork’HIT and Biotech Santé Bretagne—and 3 Medical Care and Rehabilitation (SMR) centers: the Kerpape Center, the ILDYS Foundation, and the Saint-Hélier Foundation.
• INH Lab supports digital health projects addressing all types of disabilities or loss of independence and all age groups throughout the care continuum and can conduct experiments ranging from usability testing to clinical investigations.

📍Brittany

• Led by the Reims University Hospital (CHU de Reims).
• Key consortium members: Institute for Artificial Intelligence in Healthcare (IIAS) and PETILLANTeS, Auban Moët Epernay Hospital, SOS Médecins France, Quest for Health, Kernel, Axon Cable, and Troyes Hospital.
• PEPS provides a comprehensive ecosystem to support artificial intelligence innovation projects in healthcare, guiding them toward widespread adoption and commercialization following validation through large-scale trials using real-world data.

📍Grand-Est

• Led by: Assistance Publique des Hôpitaux de Paris (AP-HP)
• Key consortium members: Medicen Paris Région, Université Paris Cité
• SANTINEL aims to accelerate the development, evaluation, and market access of innovative solutions dedicated to medical imaging: in radiology and digital pathology. It covers the 38 AP-HP hospitals and all medical indications.

📍Île-de-France

• Led by: Pitié-Salpêtrière University Hospital, APHP Sorbonne University
• Key consortium members: APHP Centre Hospital Group, Université Paris Cité HEGP Hospital, Réunion University Hospital, APHP URC Eco, Hôtel-Dieu Hospital, Calydial, France Rein, Info Rein Santé, Entends-Moi, Entreautre, Skezi, Biofutur Selas
• UNIREIN aims to co-design innovative digital solutions, test them in real-world settings and demonstrate their impact, analyze the user experience, measure the medical and economic benefits, support market access, and create a sustainable network of digital health experimentation facilities.

📍Île-de-France

• Led by: Paris Saint Joseph – Marie Lannelongue Hospitals
• Key consortium members: CPTS 14e, Marie Thérèse Health Centers, Paris Biotech Santé, École des Mines Paris - PSL
• Holistic helps foster innovation in preventive healthcare. With a strong focus on AI, startups and industry partners benefit from expert guidance and agile field settings through flexible, private, nonprofit healthcare facilities. Its approach promotes sustainable innovations with a positive impact.

📍Île-de-France

• Led by the Dijon Bourgogne University Hospital
• Key consortium members: University of Burgundy Europe, Santenov Dijon Bourgogne, France Assos Santé
• REALISTIC is dedicated to supporting the development and testing of innovative digital solutions in the field of rehabilitation and recovery, with the goal of maintaining or restoring the independence and quality of life of vulnerable individuals.

📍Burgundy-Franche-Comté

• Led by the Clermont-Ferrand University Hospital
• Key consortium members: Clermont Auvergne Innovation (a spin-off of Clermont Auvergne University), Clermont Auvergne University, VYV3 CENTICH Group, CareLine, GutyCare
• The main focus of the Tiers lieu is home healthcare 

📍Auvergne-Rhône-Alpes
 

• Led by: Foch Hospital
• Consortium members: Adolphe de Rothschild Foundation Hospital, Medicen Paris Region, University of Versailles Saint-Quentin-en-Yvelines (UVSQ) Partners: CEA, LNE, Résah, DocCity, City of Suresnes, CCI IdF
• The HTIC supports the development of digital health technologies across all activities of its member hospitals, starting with the specialties of “Head and Neck/Neurosciences” and “Women’s Health” (Femtech). It offers a comprehensive range of services from ideation to commercialization, with a focus on involving end users (doctors, healthcare providers, and patients).

📍Île-de-France
 

• Led by the Le Vinatier Hospital Center
• Key consortium members: ARHM Foundation and Adapei 69
• DIGIMENTALLY is an eco-design initiative in partnership with the Hospices Civils de Lyon and builds on three existing “Tiers lieux.” This “Tiers lieu” focuses on mental health by testing digital solutions and services in the areas of prevention, care, and recovery. 

📍Auvergne-Rhône-Alpes

• Led by: GHU Paris Psychiatry and Neurosciences
• Key consortium members: La Maison Perchée – La Poste Santé & Autonomie – GIP Sesan – Psycom – Unafam – Paul Guiraud Hospital – PariSanté Campus – Inserm
• MindLink is a space for collaboration, open to all, where everyone can share their experiences to co-design digital mental health tools with users (healthcare professionals, individuals living with mental or neurodevelopmental disorders, and caregivers).

📍Île-de-France

• Led by the Bordeaux University Hospital
• Key consortium members: Côte Basque Hospital, Charles Perrens Hospital, University of Bordeaux, CATIE, UNITEC, Aquitaine Sciences Transfert
• Station E-Santé aims to address three major challenges that must be considered when developing digital solutions that are useful and relevant to users’ health: the challenge of effectiveness, the challenge of usage, and the challenge of integration.

📍Nouvelle-Aquitaine

• Led by: ipso santé
• Consortium member: MOODS team (Center for Epidemiology and Population Health)
• The eSPoir laboratory serves as a testing ground for primary care. It combines the organizational and technological expertise of ipso santé medical practices with the methodological and clinical expertise of the MOODS team to develop digital solutions that take a holistic (somatic and mental health) approach to these challenges.

📍Île-de-France

• Led by: CHIC Castres-Mazamet
• Consortium: CPTS Sud-Tarn, EHPAD Agir, ISIS School, Gérontopôle-Toulouse University Hospital
• RI2S (Rural Innov Santé Sénior) is dedicated to testing and co-developing digital solutions for the prevention and care of seniors in rural or isolated areas. 

📍Occitania

• Led by: Center for Innovation and Health Practices (CIUS)
• Key consortium members: Assistance Publique-Hôpitaux de Marseille (AP-HM), URPS Médecins Libéraux and URPS Infirmières PACA, Fédération Hospitalière de France PACA, UGECAM PACA Corse, APF France Handicap PACA Corse, Ligue Contre le Cancer 06, Association France Diabète 06, Aix-Marseille University (AMU), SATT Sud-Est, ARS PACA, Provence-Alpes-Côte d’Azur Region...
• Le Quatre Vingt serves as a true one-stop shop for those leading innovative digital health projects. It relies on a broad network of real-world pilot sites, supported by a collaborative and methodical approach to analyzing needs and usage patterns in the field. 

📍Provence-Alpes-Côte d'Azur

• Led by the HCL (Hospices Civils de Lyon)
• Key consortium members: Pulsalys (SATT Lyon St. Etienne), Minalogic, Service d’Accès aux Soins SAS 69, Lyon Biopôle
• PLATINES focuses on emergency and unscheduled care.

📍Auvergne-Rhône-Alpes

• Led by: ipso santé
• Consortium member: MOODS team (Center for Epidemiology and Population Health)
• The eSPoir laboratory serves as a testing ground for primary care. It combines the organizational and technological expertise of ipso santé medical practices with the methodological and clinical expertise of the MOODS team to develop digital solutions that take a holistic approach (somatic and mental health) to these challenges.

📍Île-de-France

• Led by: Foch Hospital
• Consortium members: Adolphe de Rothschild Foundation Hospital, Medicen Paris Region, University of Versailles Saint-Quentin-en-Yvelines (UVSQ)
  Partners: CEA, LNE, Résah, DocCity, City of Suresnes, CCI IdF
• The HTIC supports the development of digital health technologies across all activities of its member hospitals, beginning with the specialties of “Head and Neck/Neurosciences” and “Women’s Health” (Femtech). It offers a comprehensive range of services from ideation to commercialization, with a focus on involving end users (doctors, caregivers, patients).

📍Île-de-France