Since 2011, large cohorts have been developed that can track more than one million volunteers. This data represents infrastructure that is widely open to academic and industrial collaborations.

However, several limitations have been identified:

• The fragmentation of the initiatives does not allow the project leaders to address isolated regulatory, technical, and scientific changes on their own
• There is a need for pooled effort in order to collectively meet the challenges of regulations (GDPR), security (HDS), computing (storage, calculation), and human resources (computer scientists, statisticians, etc.).
  

The objective of the action is to revitalize and perpetuate the France Cohortes infrastructure in order to obtain an interoperable catalog of data from research within 10 years, forming a possible national module that could be paired with the HDH.

In the interest of pooled efforts, the action aims to propose cross-cutting support functions to the cohorts. It will help improve the visibility of cohorts and make them sustainable: The value of a cohort is often contingent on its long-term follow-up, and they pose major challenges in terms of their sustainability.