The day, held at Ircad, began with roundtable discussions in French and English on the theme of cross-border cooperation between digital health players for seamless care pathways. The day was introduced and moderated by Jonathan Lotz, Managing Director of Pulsy, a regional support group for the development of e-health in the Grand Est region. This was followed by a video message from Jacques Marescaux, President and Founder of Ircad, who welcomed all participants. This was followed by speeches from Laurent Dal Mas, Director of Quality, Performance and Innovation at ARS Grand Est, Louisa Stüwe and David Sainati, both from the Ministerial Delegation for Digital Health at the Ministry of Health and Prevention, on the French Presidency of the Council of the European Union and the strategy for accelerating "Digital Health" respectively.

The first table on digital health for the benefit of cross-border care pathways and European initiatives was moderated by Angelica Cavalcante, Agence du numérique en santé (ANS) with several European speakers:

• Konstantin Hyppönen, DG SANTE, European Commission on the deployment of MaSanté@UE and its use cases: Patient Record, ePrescription, eDispensation;
• Hervé Barge, Director General, eSanté Agency, Luxembourg, on the deployment of MaSanté@UE in Luxembourg, including Prescription;
• Marc Loutrel, Agence du numérique en santé (ANS), France, on the deployment of MaSanté@UE in France; and
• Georgios Margetidis, European Health and Digital Executive Agency (HaDEA), European Commission, presenting recommendations for a European vaccination e-card.

Review the exchanges here.

The second round table on the subject of digital healthcare to promote cross-border cooperation and innovative territories was moderated by Dr. Sandra Chalhoub of the Grand Est innovation & international prospecting agency, Grand E-Nov+, and featured:

• For Germany: Dr. Manfred Zahorka, senior manager, OptiMedis which is the operator in charge of transforming the local healthcare system, deploying an integrated healthcare approach in a territory;
• For France: Fanny Loux, project manager on the Territoires de Santé de Demain (TSD), Eurométropole de Strasbourg and Jean-Charles Dron, operational director of the eMeuse Santé program of the Conseil Départemental de la Meuse, two structuring projects that were winners of the national call for projects "Territoires d'Innovation" whose vocation is to finance real-life testing of technologies and new services and experimental deployments of sufficient size to prefigure tomorrow's territorial development models.

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The third round table, moderated by Louisa Stüwe, focused on the use of healthcare data across borders for research and innovation to benefit care pathways. It involved researchers, private and institutional players around their research projects, and enabled the players at this table to discuss what is needed to share healthcare data on a cross-border scale to successfully conduct research projects, and specifically in the four cross-border countries of the Grand Est region. Present:

• Pr Jochen Klucken, member of the Chair of Digital Medicine, University of Luxembourg, Luxembourg;
• Catherine Commaille-Chapus, Partner, Impact Healthcare, France, on the launch of the large-scale Franco-German project AIOLOS, a real-time multi-source data collection platform based on AI and predictive modeling, whose aim is to detect an epidemic linked to a respiratory pathogen at the earliest signs, monitor its progress, take appropriate measures and assess their impact;
• Dr Domitille Boudard, Scientific Director, Neurex, France about Neurex, a trinational network in the Upper Rhine Valley dedicated to neuroscience research, and HaPpY, an international network of laboratories, clinics, companies and associations, dedicated to the study of comorbidity between chronic pain and mood disorders;
• Pr Agnès Bloch Zupan, PUPH, Faculty of Dental Surgery, University of Strasbourg, France, about several research projects, cross-border, on rare diseases, including, RARENET, an "Interreg" project of cross-border cooperation that improves the care of patients with rare autoimmune diseases and / or with oral expression through the interconnection, interaction, training and information of different actors; and
• Pr Roman Hossein Khonsari, PUPH, Hôpital Necker - Enfants Malades (AP-HP), France and Medical Director of the Health Data Hub, France, to share his daily life as a maxillofacial surgeon and in response to Prof. Bloch-Zupan, rare diseases including craniofacial malformations, and on the Health Data Hub, the national gateway for access to health data for research of general interest and moreover as leader for a European consortium to experiment with the European Health Data Space.

Review the exchanges here.

The afternoon was organized around six thematic workshops designed to deepen the exchanges of the morning's three round tables:

The first workshop was devoted to the issues and challenges of accelerating innovation in digital healthcare for startups in the Grand Est region, led by Sandra Chalhoub of Grand E-Nov+ with contributions from:

• Etienne Musquar, Grand E-Nov+ ;
• Jérôme Fabiano, EIT HEALTH;
• Guillaume Vetter-Genoud, SEMIA;
• Matis Ringdal, PIXACARE;
• Geoffrey Kretz, kwit; and
• Bérangère Henrion, H'ability.

Review the exchanges here.

Workshop 2 focused on the implementation of ePrescription in Estonia and Finland, moderated by Angelica Cavalcante of the Agence du numérique en santé (ANS), with:

• Liisa Lvova, TEHIK, Estonia; and
• Nella Savolainen, Ministry of Social Affairs and Health, Finland.

Review the exchanges here.

Workshop 3 on tomorrow's innovative territories was held by Bruno Boutteau of ARS Grand-Est with the participation of:

• Dr Manfred Zahorka, Optimedis, Germany; and
• Jean-Charles Dron, eMeuse Santé, France.

Workshop 4 offered a focus on research projects and was moderated by Louisa Stüwe of the Délégation ministérielle au numérique en santé and featuring:

• Diane Tassy, from the PF4 research and innovation office, DGOS, Ministry of Health and Prevention with an update on the PREPS (Programme de recherche sur la performance du système de soins) research program of the DGOS (Direction générale de l'offre de soins);
• Professor Gilles Chatellier, HEGP, AP-HP, vice-chairman of the PREPS selection panel on the point specifically on the prerequisites to be selected in this call for projects and particularly in relation to research projects on the subject of digital health; and
• Alban Dupoux, GIRCI EST, to explain how the Groupement Interrégional de Recherche clinique et d'Innovation Grand Est can support researchers in developing research projects.

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Workshop 5 discussed the portability of a European citizen's vaccination e-carnet and was moderated by François Kaag and his research team Dr Alain Cimini and Pr Jean-Louis Koeck and featuring:

• Georgios Margetidis, European Health and Digital Executive Agency (HaDEA), European Commission;
• Vincent Melis, Federal Ministry of Public Health, Belgium;
• Hervé Barge, Director eSanté agency, Luxembourg;
• Dr Jürgen Rissland, Saarland University Hospital, Germany;
• Patrick Jolo, eHealth, Switzerland;
• Marc Loutrel, Agence du numérique en santé (ANS), France; and
• Henri Lewalle and Denis Olivier, Economic and Social Committee, Greater Region.

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Workshop 6 focused on cross-border digital health research projects on rare diseases, moderated by Louisa Stüwe with contributions from:

• Pr Agnès Bloch Zupan, Faculty of Dental Surgery, University of Strasbourg; and
• Steve Ursprung, Vice-Chairman of the Scientific Advisory Board and "patient-expert" representative of the Hypophosphatasia Europe association.

Review the exchanges here.

Interministerial coordination warmly thanks all the participants in this event as well as the co-organizers for having actively contributed to building and setting up this ambitious and studious day, 100% European in a cross-border region par excellence, on shared topics mobilizing digital health. It is expected that this day will have provided inspiration and momentum for other cross-border collaborations to come.